The New England Journal of Medicine Review article Nora D. Volkow, M.D., Ruben D. Baler, Ph.D., Wilson M. Compton, M.D.,
and Susan R.B. Weiss, Ph.D.
Table 1. Adverse Effects of Short-Term Use and Long-Term or Heavy Use of Marijuana. |
Effects of short-term use Impaired short-term memory, making it difficult to learn and to retain infor- mation Impaired motor coordination, interfering with driving skills and increasing the risk of injuries Altered judgment, increasing the risk of sexual behaviors that facilitate the transmission of sexually transmitted diseases In high doses, paranoia and psychosis Effects of long-term or heavy use Addiction (in about 9% of users overall, 17% of those who begin use in ado- lescence, and 25 to 50% of those who are daily users)* Altered brain development* Poor educational outcome, with increased likelihood of dropping out of school* Cognitive impairment, with lower IQ among those who were frequent users during adolescence* Diminished life satisfaction and achievement (determined on the basis of subjective and objective measures as compared with such ratings in the general population)* Symptoms of chronic bronchitis Increased risk of chronic psychosis disorders (including schizophrenia) in persons with a predisposition to such disorders
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